New CSOS Subscription Manual – Certificate

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The Drug Enforcement Administration (DEA) Controlled Substance Ordering System (CSOS) allows for secure electronic transmission of controlled substance orders without the supporting paper Form 222. Since some DEA registrants may not wish to take advantage of the new regulations allowing electronic ordering, DEA will leave current regulations and current paper ordering processes in place. The adoption of CSOS standards is the only allowance for electronically signing and transmitting orders for Schedule I (CI) and II (CII) controlled substances.
Each individual requesting the ability to sign electronic orders for controlled substances must enroll with DEA. This Subscriber Manual documents enrollment with DEA in the CSOS program as well as assistance with certificate acquisition and management. Once a CSOS subscriber has enrolled with DEA and attained his/her digital certificate(s), he/she may place electronic orders of controlled substances from participating suppliers/wholesalers using CSOS approved ordering software.

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